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Advances in HIV Vaccine Research

Those poor monkeys. The National Institute of Allergy and Infectious Diseases co-funded a research that was recently published in the popular science journal Nature.

Monkey’s injected with a new experimental vaccine had an 80% to 83% decrease in risk of infection with SIV (Monkey HIV) per exposure compared to monkeys that received a placebo vaccine. Also, the monkey’s that got the vaccine and did get infected showed a substantial decrease in the amount of virus in their blood.

Scientist found that the monkeys that enjoyed the most protection developed an antibody to a part of the HIV shell called Env.

Plans are already underway to trial this vaccine in humans.

About Dr. Tan
Dr. Tan graduated from the National University of Singapore in 2001. His residency was in the two largest public hospitals in Singapore; Tan Tock Seng Hospital and Singapore General Hospital.

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16 Comments

  1. TheSillyOne

    Hi Dr. Tan, do you think hiv vaccine is possible in future? The hiv genetic matetial mutates so quickly due to its infidel copying machanism, do you think scientists can find some conserved region of the genetic material for vaccine development?

    • Good question and you obviously have a biology background. HIV vaccine development has been nothing short of dismal. There was a glimmer of hope in a Thai vaccine trial years ago but that was quickly followed by another failure. With the evidence we have now, it would seem a cure is more likely than a vaccine.

  2. Dear dr tan is it possible we are unfected by hiv by masturbating each other?? Thank u

  3. Hi doctor how to differentiate a virus fever symptom and hiv symptom..if we check for hiv 1 & 2 test when we have a virus fever what will be the result…

    • You cannot. The fact is HIV is a virus so the symptoms it causes are just like any other viral infection. If you do not have HIV, the HIV test will be negative.

  4. Russia

    a good new ?

    HIV prevention pill Truvada backed by US experts

    http://www.bbc.co.uk/news/health-18030057

  5. Russia

    At Russia, they made a new drug which is able to cure HIV. It calls Profetal which was found by Dr Rodionov Sergey Yuryevich, a Russian scientist (http://limbt.com/page/35/).

    more: http://english.ruvr.ru/2011/10/27/59453446.html?trks=936132&trkv=900632

    • Hi Russia,

      First of all the link you provided talks about Hepatitis C and not HIV. Second of all, in my personal opnion, I really despise people who make such unethical claims to further their own ends. If there is truly a drug that can cure HIV, it will be all over the international news by now. I advise you not to be taken in by such unfounded claims.

      rgds

      Dr Tan

  6. Is there any hiv vaccine available in singapore? i read from new that HIV vaccine is available somewhere in singapore…

    THanks

    • Hi medical health,

      Can you please provide us with the link to that piece of news. Or if it is print, please scan it and email it to me. I want everyone to know of the publishers of such damaging and malicious rumours. Vaccine development has seen many advances recently but there is certainly no vaccine available yet either in Singapore or anywhere else in the world.

      rgds

      Dr Tan

  7. 醫師你好:
    因為我的英文能力不好,所以需要以中文向您提問
    我的狀況如下:
    1.我在2011/11/26號,有與一位泰國女子危險性交,僅放入約5~10秒(感覺對方陰道裡面很乾燥),之後將手指伸入女方陰道指交,直到對方陰道有大量分泌物,之後戴上套子完成性交。
    2 我在2011/12/6 ,與另一名泰國女子有帶保險套性交,但我是一個毛囊炎患者,在屁股,以及性器官的上方(恥毛處)有大量毛囊炎傷口,如果對方的陰道分泌物大量的流在毛囊炎的部位,會有可能得到hiv嗎?
    最後補充
    我個人在12/10號,在泰國康明醫院檢驗ab/ag,陰性。
    第一名泰國女子在12/31,CMIA檢驗,陰性。
    第二名泰國女子在2012/1/2,Ela陰性。
    我又在1/4,非康明醫院,抗體檢查,陰性。
    然後 1/5 Bangkok savetivaj hospital pcr 陰性。

    請問,我還需要三個月去複檢嗎?? 我是否已經排除了危機呢??
    非常感謝醫生你的協助
    祝你新年快樂,萬事如意!

    • Hi OMG,

      您的爱滋病病毒抗体测试,是您曝光的4周后进行。这是好的,但不是决定性的。你必须得到您曝光3个月后再测试.

      rgds

      Dr Tan

  8. Hi Dr.

    Thanks for the sharing.

    It is a great news. Hope this vaccine will be succeeded so that more HIV patient can benefit from it.

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